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微波法合成熊果酸衍生物
引用本文:甘,亚,廖洪利,吴,也,夏春勇,王武强.微波法合成熊果酸衍生物[J].化学与生物工程,2014(3):38-39.
作者姓名:    廖洪利      夏春勇  王武强
作者单位:成都医学院药学院,四川成都610083;四川省广安市人民医院药剂科四川广安638000
基金项目:成都医学院大学生创新实验项目(CX2010026)
摘    要:以熊果酸为原料,分别通过常规方法及微波法合成3-O-乙酰基熊果酸和熊果酸丁酯,并经核磁共振氢谱确证其化学结构。结果表明,微波法大大缩短了反应时间,提高了收率。

关 键 词:微波法  合成  熊果酸  衍生物

Synthesis of Ursolic Acid Derivatives by Microwave Method
GAN Ya,LIAO Hong-li,WU Ye,XIA Chun-yong,WANG Wu-qiang.Synthesis of Ursolic Acid Derivatives by Microwave Method[J].Chemistry & Bioengineering,2014(3):38-39.
Authors:GAN Ya  LIAO Hong-li  WU Ye  XIA Chun-yong  WANG Wu-qiang
Affiliation:1.School of Pharmacy ,Chengdu Medical College, Chengdu 610083 ,China ;Department of Pharmacy ,Guang'an Municipal People's Hospital ,Guang'an 638000, China;)
Abstract:Using ursolic acid as starting material,3-O-acetyl ursolic acid and ursolic acid butyl ester were synthesized by conventional method and microwave method,and their structures were confirmed by 1HNMR.The results showed that the reaction time was shortened and the yield was improved by the microwave method.
Keywords:microwave method  synthesis  ursolic acid  derivative
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