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维生素D与甲状腺疾病的相关性
引用本文:苏姗,张迪,王强梅,甄东户. 维生素D与甲状腺疾病的相关性[J]. 金属学报, 2020, 25(1): 94-100. DOI: 10.12092/j.issn.1009-2501.2020.01.014
作者姓名:苏姗  张迪  王强梅  甄东户
作者单位:1.兰州大学第一临床医学院,兰州 730000,甘肃;;2.兰州大学第一医院内分泌科,兰州 730000,甘肃
基金项目:甘肃省自然科学基金(1606RGZA347);中央高校基本科研业务费专项资金重点项目(2022142zrk012);甘肃省卫生行业科研计划(GSWSKY-2014-27);兰州大学第一医院院内基金(ldyyyn-2015-23)
摘    要:维生素D除了具有调节钙磷及骨代谢作用外,免疫调节及抗肿瘤增殖作用逐渐被研究者们提出。目前,大量研究发现患有甲状腺疾病的患者体内维生素D水平较低,并认为维生素D不足/缺乏可能参与甲状腺疾病的发病过程,但二者之间具体的关系及作用机制尚未完全明确。本文旨在对近几年关于维生素D与几种常见的甲状腺疾病相关性的研究进行综述,分析维生素D在甲状腺疾病发病中的作用,以及补充维生素D对甲状腺疾病发生、发展的影响。

关 键 词:维生素D   Graves病   桥本氏甲状腺炎   甲状腺结节   甲状腺癌  
收稿时间:2019-10-28
修稿时间:2019-12-10

Correlation between vitamin D and thyroid disease
SU Shan,ZHANG Di,WANG Qiangmei,ZHEN Donghu. Correlation between vitamin D and thyroid disease[J]. Acta Metallurgica Sinica, 2020, 25(1): 94-100. DOI: 10.12092/j.issn.1009-2501.2020.01.014
Authors:SU Shan  ZHANG Di  WANG Qiangmei  ZHEN Donghu
Affiliation:1.The First Clinical Medical College of Lanzhou University, Lanzhou 730000, Gansu, China;2.Department of endocrinology, the First Hospital of Lanzhou University, Lanzhou 730000, Gansu, China
Abstract:In addition to the role of vitamin D in regulating calcium and phosphorus homeostasis and bone metabolism, immune regulation and anti-tumor proliferation have been gradually proposed by researchers. At present, a large number of studies have found that patients with thyroid diseases have low vitamin D levels, and it is believed that vitamin D insufficiency/ deficiency may be involved in the pathogenesis of thyroid diseases, but the specific relationship and mechanism between vitamin D and thyroid diseases have not been fully clarified. This article reviewed in the relationship between vitamin D and several common thyroid diseases in recent years, in order to analyze the role of vitamin D in the pathogenesis of thyroid diseases, as well as the influence of vitamin D supplementation on the occurrence and development of thyroid diseases.
Keywords:vitamin D   Graves' disease   Hashimoto's thyroiditis   thyroid nodules   thyroid cancer  
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