硝基苯锌法合成对氨基苯酚的研究

研究了硝基苯经锌粉还原为苯基羟胺，在无需分离和纯化的条件下经重排和精制得到对氨基苯酚，其质量达到了制药原料标准，同时副产高纯度氧化锌。还研究了反应条件和试验操作对收率和产品质量的影响。在优化的反应条件下获得了具有工业应用价值的结果

Preparation of p Aminophenol by the Reduction of Nitrobenzenewith Zinc Powder

　new　method　for　the　preparation　of　p aminophenol(PAP)　has　been　developed　by　the　reduction　of　nitrobenzene　with　zinc　powder　in　aqueous　ammonium　chlorideThe　rearrangement　of　phenylhydroxylamine　formed　during　the　reduction　is　carried　out　in　dilute　sulfuric　acid　without　the　need　of　isolation　and　purificationThe　quality　of　PAP　has　attained　that　for　medical　applications,and　highly　pure　zinc　oxide　is　obtained　as　a　by productThe　effects　of　the　reaction　conditions　and　operation　factors　on　the　yield　and　quality　of　PAP　are　also　studiedThe　results　showed　that　the　method　has　industrial　value