Biliary colonic ileus: an unusual cause of colonic obstruction] |
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| Authors: | G Bornet H Chiavassa D Galy-Fourcade T Jarlaud N Sans F Labbé JL Gouzy JJ Railhac |
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| Affiliation: | Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Co., Ann Arbor, MI 48105, USA. |
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| Abstract: | PD 108635 (1) was identified as a potent dopamine D4 ligand and we wanted to replace the benzylic alcohol with a metabolically more stable moiety. Investigations led to the discovery of a series of isoindolinones having D4 affinity. |
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