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抗菌肽功能特性与作用机制的研究进展
引用本文:康媛媛,孟珺,王艳阳,章绍兵. 抗菌肽功能特性与作用机制的研究进展[J]. 食品科技, 2021, 0(1)
作者姓名:康媛媛  孟珺  王艳阳  章绍兵
作者单位:河南工业大学粮油食品学院
基金项目:河南省属高校基本科研业务费专项资金自然科学项目(2017QNJH14)。
摘    要:抗菌肽是核糖体合成的天然抗生素,是多细胞生物体免疫系统的一部分。抗菌肽的来源广泛,氨基酸的组成和结构差异很大,具有快速杀伤以及广谱的抗菌活性。随着抗菌肽种类越来越多,对其抗菌机制及构效关系的研究成为学者们关注的热点。文章系统地阐述了抗菌肽的来源和功能特性、抑菌机制以及构效关系。

关 键 词:抗菌肽  来源  功能特性  抑菌机制  构效关系

Research Progress on Functional Characteristics and Mechanism of Antimicrobial Peptides
KANG Yuanyuan,MENG Jun,WANG Yanyang,ZHANG Shaobing. Research Progress on Functional Characteristics and Mechanism of Antimicrobial Peptides[J]. Food Science and Technology, 2021, 0(1)
Authors:KANG Yuanyuan  MENG Jun  WANG Yanyang  ZHANG Shaobing
Affiliation:(College of Food Science and Technology,Henan University of Technology,Zhengzhou 450052,China)
Abstract:Antimicrobial peptides are natural antibiotics synthesized by ribosome and a part of the immune system of multicellular organisms.Antimicrobial peptides come from a wide range of sources and have different amino acid composition and structure.They always have rapid killing and broad-spectrum antimicrobial activity.With the increasing variety of antimicrobial peptides,the research on their antimicrobial mechanism and structure-activity relationship has become a hot topic.In this paper,the source,functional characteristics,antibacterial mechanism and structure-activity relationship of antimicrobial peptides were systematically discussed.
Keywords:antibacterial peptide  source  functional features  bacteriostatic mechanism  structure-activity relationship
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