| 解热止痛片中3种成分的分离及其波谱研究 |
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| 引用本文： | 秦向东,裴静,沈建红,孙淑萍,王学琳. 解热止痛片中3种成分的分离及其波谱研究[J]. 现代仪器, 2001, 0(4): 31-34 |
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| 作者姓名： | 秦向东 裴静 沈建红 孙淑萍 王学琳 |
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| 作者单位： | 首都师范大学化学系,北京,100037 |
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| 摘 要： | 用薄层色谱波对解热止痛片(APC片)中3和成分进行了分离,展开了剂为苯-乙醚-冰乙酸-甲醇(120∶60∶18∶1),展开结果:阿斯匹林Rf=0.84,非那西汀Rf=0.46,咖啡因Rf=0.17。对分离产物进行了FT-IR和PFT-H-NMR研究,结果表明,分离产物纯度较高。分离充分,效果满意。
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| 关 键 词： | 薄层色谱 解热止痛片 红外 核磁 |
Separation and spectrum study of 3 components in Aspirin Tablefs |
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| Qin Xiangdong,Pei Jing,Shen Jinghong,Sun Shuping,Wang Xuelin. Separation and spectrum study of 3 components in Aspirin Tablefs[J]. Modern Instruments, 2001, 0(4): 31-34 |
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| Authors: | Qin Xiangdong Pei Jing Shen Jinghong Sun Shuping Wang Xuelin |
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| Abstract: | Three components (aspirin, phenacein and caffeine) in APC tablets were separated by thin layer chro-matography with the mobile phase consisting benzene-ether-acetic acid-methanol (180:60:18:1), then determined by IR and NMR. The result was: aspirin Rf=0. 84; phenacetin Rf = 0. 46, caffeine Rf=0. 17. A thorough separation was proved by IR and NMR spectrum. The method was simple, rapid and reliable. |
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| Keywords: | thin layer chromatography APC tablets IR NMR |
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