| 光子嫩肤热损伤的光学相干层析成像动态监控 |
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| 引用本文： | 黄义梅,龚玮,谢树森.光子嫩肤热损伤的光学相干层析成像动态监控[J].光电子．激光,2009,20(5). |
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| 作者姓名： | 黄义梅 龚玮 谢树森 |
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| 作者单位： | 福建师范大学激光与光电子技术研究所,福建省光子技术重点实验室,医学光电科学与技术教育部重点实验室,福建,福州,350007
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| 摘 要： | 提出了一种基于光学相干层析成像(PCT)的动态监控光子嫩肤热损伤的系统.利用OCT测试系统的非入侵性无损检测的技术特点进行实时测量光子嫩肤治疗过程中皮肤的光学参数,并根据所获得的光学参数变化量来反映热损伤程度.采用小鼠动物模型,并用不同剂量的激光照射小鼠背部皮肤,得到了皮肤组织的衰减系数将随着光剂量的增大而减小的关系.实验结果表明,衰减系数的变化量反映了热损伤的严重程度.
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| 关 键 词： | 医用光学与生物技术 热损伤动态监控 光学相干层析成像(OCT) 选择性光热解 非消融性光子嫩肤 |
Monitoring thermal damaged tissue in photorejuvenation with optical coherence tomography |
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| HUANG Yi-mei,GONG Wei,XIE Shu-sen.Monitoring thermal damaged tissue in photorejuvenation with optical coherence tomography[J].Journal of Optoelectronics·laser,2009,20(5). |
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| Authors: | HUANG Yi-mei GONG Wei XIE Shu-sen |
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| Affiliation: | Key Laboratory of Optoelectronic Science and Technology for Medicine of EMC Key Laboratory for Photonics Technology of Fujian Provinical;Institute of Laser and Optoelectronics Technology;Fujian Normal University;Fuzhou 350007;China |
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| Abstract: | A system based on optical coherence tomography(OCT) is presented,which can monitor dynamically the thermal damaged tissue during laser irradiation in photorejuvenation.With the advantage of the noninvasive characteristics of the OCT,this system can measure in vivo the optical parameters of skin during the therapy and evaluate the degree of the thermal damage according to the change of the optical parameters.Various laser light doses are irradiated on the back skins of the mice.The relationship between the t... |
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| Keywords: | medical optics and biotechnology monitor dynamically thermal damage optical coherence tomography(OCT) selective thermolysis non-ablative photorejuvenation |
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