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A clinical and histological comparative study of the effect of nifedipine and phenytion on human gingiva
Authors:MA Shoieb  LM Fathy  O Abu-el-Dahab  MM el-Sherbiny
Affiliation:Faculty of Oral and Dental Medicine, Cairo University, Egypt.
Abstract:Ten patients manifesting gingival enlargement were chosen for this study. Five patients had been treated with 4 mg nifedipine per day as a treatment for angina pectoris, while the other five patients treated with phenytion as an anticonvulsant drug. Clinical and histological data showed that nefidipine induced gingival hyperplasia which is of close similarity to that induced by phenytion despite the differences in target tissue.
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