A hybrid artificial immune algorithm for a realistic variant of job shops to minimize the total completion time

This paper investigates an extended problem of job shop scheduling to minimize the total completion time. With aim of actualization of the scheduling problems, many researchers have recently considered realistic assumptions in their problems. Two of the most applied assumptions are to consider sequence-dependent setup times and machine availability constraints (MACs). In this paper, we deal with a specific case of MACs caused by preventive maintenance (PM) operations. Contrary to the previous papers considering fixed or/and conservative policies, we consider flexible PM operations, in which PM operations may be postponed or expedited as required. A simple technique is employed to schedule production jobs along with the flexible MACs caused by PM. To solve the given problem, we present a novel meta-heuristic method based on the artificial immune algorithm (AIA) incorporating some advanced features. For further enhancement, the proposed AIA is hybridized with a simple and fast simulated annealing (SA). To evaluate the proposed algorithms, we compare our proposed AIA with three well-known algorithms taken from the literature. Finally, we find that the proposed AIA outperforms other algorithms.