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| 除草剂噻磺隆的合成 | |
| 引用本文： | 陆阳,李春仁,池慧,陶京朝,张志荣.除草剂噻磺隆的合成[J].现代农药,2006,5(5):22-24. |
| 作者姓名： | 陆阳 李春仁 池慧 陶京朝 张志荣 |
| 作者单位： | 1. 郑州大学化学系,郑州,450001;信阳农业高等专科学校,河南,信阳,464000 2. 信阳职业技术学院,河南,信阳,464000 3. 安徽省华祥农药化工公司,合肥,230041 4. 郑州大学化学系,郑州,450001 |
| 摘 要： | 报道了以氯甲酸甲酯和2-甲氧羰基-3-氨基磺酰基噻吩为起始原料合成除草剂噻磺隆的方法。原料2-甲氧羰基-3-氨基磺酰基噻吩与氯甲酸甲酯生成2-甲氧羰基-3-甲氧羰基氨基磺酰基噻吩,再与2-氨基-4-甲氧基-6-甲基均三嗪反应生成噻磺隆。避免了异氰酸酯路线的种种缺点,具有收率高、含量高、成本低的特点。以2-甲氧羰基-3-氨基磺酰基噻吩计,总收率为77.73%,原药纯度达93.6%。 |
| 关 键 词： | 噻磺隆 氯甲酸甲酯 磺酰脲 除草剂 |
| 文章编号： | 1671-5284（2006）05-0022-03 |
| 收稿时间： | 2006-06-01 |
| 修稿时间： | 2006-08-14 |
Synthesis of Herbicide Thifensulfuron |
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| LU Yang,LI Chun-ren,CHI Hui,TAO Jing-zhao,ZHANG Zhi-rong.Synthesis of Herbicide Thifensulfuron[J].Modern Agrochemicals,2006,5(5):22-24. | |
| Authors: | LU Yang LI Chun-ren CHI Hui TAO Jing-zhao ZHANG Zhi-rong |
| Affiliation: | 1. Chemistry Department of Zhengzhou University, Zhengzhou 450001, China; 2. Xinyang Agriculture College, Henan Xinyang 464000, China; 3. Chemical Engineering Department of Xinyang Vocational and Technical College, Henan Xinyang 464000, China; 4. Anhui Province Huaxiang Pesticides Chemical Engineering Company, Hefei 230041, China |
| Abstract: | A method for preparation of thifensulfuron from methyl chloroformate and 2-methoxycarbonyl-3- aminosulfonylthiophene as starting material was reported. 2-Methoxycarbonyl-3-aminosulfonylthiophene reacts with methyl chloroformate to give 2-methoxycarbonyl-3-methoxycarbonyl aminosulfonylthiophene. Thifensulfuron will be obtained by the reaction of the above product and 2-amino-4-methoxy-6-methyl-1,3,5-triazine. This is an economical method to prepare thifensulfuron in high yield and good purity, avoiding the shortcoming of the isocyanate route. The total yield reaches 77.73% based on 2-methoxycarbonyl-3-aminosulfonylthiophene and the purity is 93.6%. |
| Keywords: | thifensulfuron methyl chloroformate sulfonylureas herbicide |
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