Pt/C催化加氢3-氯-4-甲基硝基苯制备3-氯-4-甲基苯胺

3-氯-4-甲基苯胺是合成有机颜料、染料和农药的重要有机中间体。以3-氯-4-甲基硝基苯为原料,1%Pt/C为催化剂,低压催化加氢制备3-氯-4-甲基苯胺,考察不同溶剂、反应压力、反应温度和催化剂用量对产物收率的影响。结果表明,在3-氯-4-甲基硝基苯10 g、溶剂甲醇用量30 m L、1%Pt/C催化剂用量0.04 g、反应温度80℃和反应压力1.0 MPa条件下,3-氯-4-甲基苯胺收率99.08%,脱氯率0.2%,催化剂可重复使用5次。

Catalytic hydrogenation of 3-chloro-4-methylnitrobenzene to 3-chloro-4-methylaniline over Pt/C catalyst

3-Chloro-4-methylaniline is an important organic intermediate for the synthesis of organic pigments,dyes and pesticides.3-chloro-4-methylaniline was synthesized by low pressure catalytic hydrogenation of 3-chloro-4-methylnitrobenzene over 1%Pt/C catalyst.The effects of different solvents, reaction pressure, reaction temperatures and catalyst amount on the product yield were investigated. The results showed that 3-chloro-4-methylaniline yield of 99.08% and the dechlorination rate of 0.2% were obtained under the condition of 3-chloro-4-methylnitrobenzene 10 g,methanol 30 mL,1%Pt/C catalyst 0.04 g,reactiontemperature 80 ℃ and reaction pressure 1.0 MPa. The catalyst could be reused five times.