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利福霉素SV高产菌株0124-8~#的选育
引用本文:赵妍,盛岩,李锐.利福霉素SV高产菌株0124-8~#的选育[J].辽宁化工,2009,38(11):794-795.
作者姓名:赵妍  盛岩  李锐
作者单位:沈阳抗生素厂,辽宁,沈阳,110122
摘    要:以现有生产菌株11#为出发菌株,进行硫酸链霉素抗性诱变。采用梯度平板及琼脂块法筛选,得到0124-8#菌株。试验结果表明,其发酵单位大幅度提高,较出发菌株提高了8.9%,并且其遗传稳定性较好。

关 键 词:地中海诺卡氏菌  利福霉素SV  硫酸链霉素抗性

Selective Breeding of Rifamycin SV high Production Strain 0124-8#
ZHAO Yan,SHENG Yan,LI Rui.Selective Breeding of Rifamycin SV high Production Strain 0124-8#[J].Liaoning Chemical Industry,2009,38(11):794-795.
Authors:ZHAO Yan  SHENG Yan  LI Rui
Affiliation:(Shenyang Antibiotic Manufacturer, Shenyang 110122, China)
Abstract:The current producted strain 11 # was chosen as the starting strain for mutagenic treatment with streptomycin sulfate resistant rational screening.The 0124-8# strain was gained by the gradient plate method and the agar block method.The results show that its fermentation unit is increased by 8.9% than the starting strain,and its genetic stability is good,too.
Keywords:Nocardia Mediterranean  Rifamycin SV  Streptomycin sulfate resistance
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