衣康酸发酵工艺的初步研究

以土曲霉为出发菌株，探讨了衣康酸发酵工艺条件对产酸的影响。结果表明：以葡萄糖为碳源，ＮＨ４ＮＯ３为氮源，玉米浆为辅助碳源有利于提高产酸。Ｍｇ２＋能促进菌体生长和发酵产酸，Ｐｂ２＋和Ａｌ３＋抑制菌体生长及产酸。Ｍｇ２＋可以解除Ｐｂ２＋和Ａｌ３＋对产酸的抑制作用。Ｍｎ２＋、Ｚｎ２＋、Ｃａ２＋、Ｃｕ２＋等对产酸影响不明显。

Studied on the Itaconic Acid Fermentation

The effects of fermentation conditions on the production of itaconic acid by Aspergillus terrus were studied.The results showed: it improved the production of itaconic acid when glucose acted as carbon source ,NH4NO3 as nitrogen source and liquid of corn seed as auxiliary nitrogen source.It was also found the addition of Mg2 increased the growth of mycelia and the itaconic acid production.Contrarily,Pb2 and Al3 inhibited the growth of mycelia and the itaconic acid production.However,the inhibition of Pb2 or Al3 would be released by the addition of Mg2 .And there were no obvious effects on the production of itaconic acid when adding Mn2 , Zn2 ,Ca2 ,Cu2 .