Ultrasonic-assisted synthesis and strepavidin conjugation of amino-magnetic nanoparticles |
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| Authors: | LIU Li JIAO Qinghua PENG Cheng HE Shijiang WANG Lihua |
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| Affiliation: | 1. School of Materials Science and Engineering, Shanghai University, Shanghai 201800, China
2. Shanghai Institute of Applied Physics, Chinese Academy of Sciences, Shanghai 201800, China |
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| Abstract: | MNPs are widely used in biotechnology, magnetic resonance imaging, catalysis and other areas. In this paper, we propose a simple, quick, inexpensive and efficient way to prepare amino-MNPs with sonication-assisted process. The amino-MNPs prepared by hydrolyzing TEOS and APS were characterized by SEM, TEM and FTIR. Conjugation of SA and amino-MNPs was also studied. The biotin bound capacity of prepared SA coated amino-MNPs was 1.824 nmol/mg, which well meet the need of biological application. |
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| Keywords: | Magnetic nanoparticles Strepavidin Biotin bound capacity Sonication-assisted surface treatment |
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