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Density of crystalline lens and cornea in different trimesters of pregnancy
Affiliation:1. Selcuk University Faculty of Medicine, Department of Opthalmology, Konya, Turkey;2. Midyat State Hospital, Department of Ophthalmology, Mardin, Turkey;3. Sutcu Imam University Faculty of Medicine, Department of Obstetric and Gynecology, Kahramanmaras, Turkey;4. Sutcu Imam University Faculty of Medicine, Department of Opthalmology, Kahramanmaras, Turkey;5. Private American Hospital, Gaziantep, Turkey;1. Department of Biotechnology and Biosciences, University of Milano - Bicocca, Piazza della Scienza 2, I-20126, Milan, Italy;2. Department of Materials Science, University of Milano - Bicocca, Via R. Cozzi 55, I-20125, Milan, Italy;3. Optic and Optometry Center of the University of Milano - Bicocca (COMiB), Italy;1. University Hospital of Wales, UK;2. Princess of Wales Hospital, UK;3. University of Ulster, UK;4. Siena Eye Laser Centre, Italy;1. Centre for Ocular Research & Education, School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, Canada;2. School of Optometry and Vision Science, University of Waterloo, 200 University Avenue West, Waterloo, N2L 3G1, Canada;3. School of Optometry and Vision Sciences, Cardiff University, Maindy Rd, Cardiff, CF24 4HQ, United Kingdom;1. Ahalia School of Optometry, Ahalia Foundation Eye Hospital, Palakkad 678557, India;2. Ahalia Foundation Eye Hospital, Palakkad 678557, India;1. Institute of Applied Ophthalmobiology (IOBA)-University of Valladolid, Valladolid, Spain;2. Department of Theoretical Physics, Atomic and Optics, University of Valladolid, Valladolid, Spain;3. Networking Research Center on Bioengineering Biomaterials and Nanomedicine (CIBER-BBN), Valladolid, Spain;4. Redes temáticas de investigación cooperativa en salud (Oftared), Instituto de Salud Carlos III, Madrid, Spain
Abstract:PurposeTo evaluate topographic measurements of the anterior segment and densitometric measurements of the cornea and lens by Pentacam HR in different trimesters of pregnancy.MethodsThis prospective study included 150 healthy pregnant women in their first, second, or third trimester (Groups 1, 2 and 3, respectively) and 54 non-pregnant healthy women (Group 0). Topographic measurements, including central corneal thickness (CCT), corneal volume (CV), anterior chamber depth (ACD), corneal densitometry (CD) and lens densitometry (LD), were done with the Pentacam HR (Oculus, Wetzlar, Germany). The measurement results of the healthy pregnant women and non-pregnant healthy women were compared.ResultsCD values were found in Group 1 to be 13.19, in Group 2 to be 13.16, in Group 3 to be 13.17 and in Group 0 to be 13.22 (p = 0.811). The mean Group 1, Group 2, Group 3 and Group 0 LD-horizontal was 5.40 ± 0.5, 5.47 ± 0.38, 5.53 ± 0.44, 5.36 ± 0.43, respectively. The mean Group 1, Group 2, Group 3 and Group 0 LD-vertical was 5.6 ± 0.43, 5.66 ± 0.32, 5.71 ± 0.40 and 5.5 ± 0.44, respectively. Area LD values were higher in the advanced trimester period, and the only statistically significant difference was between Group 3 and Group 0 (p = 0.025). The difference between three-dimensional (3D) and peak LD values was not statistically significant between the groups (p = 0.89 and p = 0.91, respectively).DiscussionThe Pentacam HR seems to be an important option for the evaluation of LD, CD and topographic measurements of the anterior segment in pregnancy. In the present study, CD and LD, including LD-horizontal, LD-vertical, peak and 3D values, were not significantly different between pregnant women and non-pregnant women.
Keywords:Lens densitometry  Corneal densitometry  Pentacam HR  Pregnancy
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