Videokeratoscopic assessment of silicone hydrogel contact lens wettability using a new in-vitro method |
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| Affiliation: | 1. École d’optométrie, Université de Montréal, PO Box 6128, Downtown station, Montreal, Quebec, Canada;2. Center for Ocular Research and Education, University of Waterloo, Canada;3. Bibliothèque de la santé, Université de Montréal, Canada;1. School of Optometry, University of Alabama at Birmingham, Birmingham, AL, USA;2. College of Optometry, The Ohio State University, Columbus, OH, USA;3. College of Optometry, University of Houston, Houston, TX, USA;4. JENVIS Research c/o Ernst Abbe University of Jena, Jena, DE, USA;5. Southern College of Optometry, Memphis, TN, USA;6. Southern California College of Optometry, Marshall B Ketchum, Fullerton, CA, USA;7. Centre for Ocular Research and Education (CORE), School of Optometry and Vision Science, University of Waterloo, Waterloo, ON, CA, USA;1. University of Alabama at Birmingham, School of Optometry, 1716 University Blvd., Birmingham, AL, USA;2. Cornea Service, New England Eye Center, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA;3. Center for Translational Ocular Immunology, Department of Ophthalmology, Tufts Medical Center, Tufts University School of Medicine, Boston, MA, USA;4. Kentucky Eye Institute, 601 Perimeter Drive, Lexington, KY, USA;1. University of Maastricht, Maastricht, The Netherlands;2. Microlens Contact Lens Technology, Arnhem, The Netherlands;1. School of Optometry and Vision Science, Faculty of Health, Institute of Health and Biomedical Innovation, Queensland University of Technology,60 Musk Avenue, Kelvin Grove, QLD 4059 Australia;2. School of Optometry and Vision Science, Faculty of Science, Rupert Myers Building, Barker Street, Kensington, NSW 2033 Australia |
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| Abstract: | PurposeThe aim of the study was to assess the surface wettability of new-generation silicone hydrogel (SiH) contact lenses (CLs) videokeratoscopically using a new in-vitro method under office conditions.MethodVideokeratoscopic methodology was used to compare time-dependent CL wettability on an in-vitro cornea model. The model cornea was a polished chrome surface coating a Teflon form. It was prepared with a base curve of 8.7 mm and a diameter of 15 mm. Laboratory temperature and humidity were controlled. Before and after placing CLs on the on the model cornea, Bausch + Lomb Biotrue® multi-purpose solution (MPS) was dropped to simulate the pre-lens and post-lens film layer. Fanfilcon A, Senofilcon A, Samfilcon A, and Lotrafilcon B CLs with -3.00D were used, and images were taken with the videokeratoscopic method for testing. In the control group, the same procedure was performed without placing CLs. The images of CLs at 0, 60, 90, 120, 150, and 180 s were taken. Distortions and gaps seen in rings were recorded. The areas in rings were calculated in pixels using ?mageJ.ResultsWhen CLs were examined, statistical differences were found among average pixel values (p < 0,001). The average pixel value was 131877.4 in the Samfilcon group, 116125.5 in the Senofilcon group, 137893.2 in the Fanfilcon group, 125578.3 in the Lotrafilcon group, and 124984.6 in the control group. No difference was found between the average values of the Lotrafilcon group and the control group. Differences were found between the average values of all other groups.DiscussionThe results obtained showed that videokeratoscopy was an effective method for in-vitro testing of CL wettability. It was found that SiH lenses displayed different performance under office conditions depending on materials and technologies used for wetting the lens surface. It was shown that lens surface wettability could be measured with a repeatable and new method when the factors affecting surface wetness and image quality were ruled out. |
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| Keywords: | Contact lens wettability Office conditions In-vitro method Videokeratoscopic method |
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