| Extending Bragg peak of heavy ion beam and melanoma cell inactivation measurement |
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| 作者姓名： | LiQiang WeiZeng－Quan |
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| 作者单位： | [1]InstituteofModernPhysics,theChineseAcademyofSciences,Lanzhou730000 [2]InstituteofModernPhysics,theChines |
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| 摘 要： | A rotating range modulator was designed and manufactured.which is applied to extend Bragg peak of heavy ion beam.Bragg curves of 75MeV/u ^16O and 75MeV/u ^12C ion beams through this range modulator were measured respectively and two evident spread-out Bragg peaks corresponding to the modulated beams above are shown.In addition,inactivation effect of the modulated 75MeV/u ^16O ion beam at nine different penetration depths on melanoma cells(B16) was measured.Results indicate that lethal effects at the spread-out Bragg peak region are larger than at the plateau of the particle beam entrance.
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| 关 键 词： | 重离子束 黑素瘤细胞 钝化作用 |
Extending Bragg peak of heavy ion beam and melanoma cell inactivation measurement |
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| Li Qiang,Wei Zeng Quan,Li Wen Jian,Zhou Guang Ming,Dang Bing Rong,Cai Xi Chen,He Jing,Xie Hong Mei,Han Guang Wu,Huang Tao,Chen Wei Qiang,Wang Ju Fang and Zhang Shu Min.Extending Bragg peak of heavy ion beam and melanoma cell inactivation measurement[J].Nuclear Science and Techniques,1998,9(1):8-10. |
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| Authors: | Li Qiang Wei Zeng Quan Li Wen Jian Zhou Guang Ming Dang Bing Rong Cai Xi Chen He Jing Xie Hong Mei Han Guang Wu Huang Tao Chen Wei Qiang Wang Ju Fang and Zhang Shu Min |
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| Abstract: | A rotating range modulator was designed and manufactured, which is applied to extend Bragg peak of heavy ion beam. Bragg curves of 75 MeV/u 16 O and 75 MeV/u 12 C ion beams through this range modulator were measured respectively and two evident spread out Bragg peaks corresponding to the modulated beams above are shown. In addition, inactivation effect of the modulated 75 MeV/u 16 O ion beam at nine different penetration depths on melanoma cells (B 16 ) was measured. Results indicate that lethal effects at the spread out Bragg peak region are larger than at the plateau of the particle beam entrance. |
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| Keywords: | Heavy ions Spread out Bragg peak Range modulator |
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