癃闭舒胶囊联合盐酸坦索罗辛治疗慢性非细菌性前列腺炎105例

目的观察癃闭舒胶囊联合盐酸坦索罗辛治疗慢性非细菌性前列腺炎(CAP)的有效性与安全性。方法治疗组60例患者给予癃闭舒胶囊与盐酸坦索罗辛,对照组45例患者给予前列康片与盐酸坦索罗辛,均连续用药4周。治疗前后分别观察NIH-CPSI、最大尿流率(MFR)、平均尿流率(AFR)、前列腺肛门指诊(DRE)、EPS。采用美国国立卫生研究院(NIH)制定的前列腺炎症状评分(CPSI)标准判定疗效。结果治疗组临床治愈率48.33%,总有效率95.00%,对照组临床治愈率和总有效率分别为37.78%,86.67%,两组比较有显著性差异(P<0.05)。两组治疗前后NIH-CPSI积分及EPS中WBC、pH值与尿流率均有不同程度的改善,但治疗组的NIH-CPSI积分与尿流率改善最显著(P<0.05)。结论癃闭舒胶囊联合坦索罗辛治疗慢性非细菌性前列腺炎有效、安全。

Clinical observation of Longbishu combined with Tamsulosin Hydrochloride in the treatment of 105 chronic abacterial prostatitis patients

Objective To observe the efficacy and safety of Longbishu combined with Tamsulosin Hydrochloride in the treatment of chronic abacterial prostatitis.Methods 60 patients in the trial group were treated with Longbishu combined with Tamsulosin Hydrochloride.and 45 patients in the control group were treated with Qianlie kang combined with Tamsulosin Hydrochloride.The NIH-CPSI,MFR,AFR,DRE and EPS were observed before and after a 4-week treatment.The efficacy was evaluated by the NIH Chronic Prostatitis Symptom Index(CPSI).Results The total improved was 95.00% in the trial group and 86.67% in the control group(P<0.05),the improvement of NIH-CPSI overall scores and urine flow rate was significant between the two groups(P<0.05).Conclusion The combined use of Longbishu and Tamsulosin Hydrochloride is effective and safe in the treatment of chronic abacterial prostatitis.