Simultaneous Measurement of Thermophysical Properties of Tissue-Mimicking Phantoms for High Intensity Focused Ultrasound (HIFU) Exposures |
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Authors: | Jing Gao Jiang You Zhihong Huang Sandy Cochran George Corner |
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Affiliation: | 1.School of Engineering, Physics and Mathematics,University of Dundee,Dundee,UK;2.Institute for Medical Science and Technology,University of Dundee,Dundee,UK;3.Department of Medical Physics,Ninewells Hospital,Dundee,UK |
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Abstract: | Tissue-mimicking phantoms, including bovine serum albumin phantoms and egg white phantoms, have been developed for, and in
laboratory use for, real-time visualization of high intensity focused ultrasound-induced thermal coagulative necrosis since
2001. However, until now, very few data are available concerning their thermophysical properties. In this article, a step-wise
transient plane source method has been used to determine the values of thermal conductivity, thermal diffusivity, and specific
heat capacity of egg white phantoms with elevated egg white concentrations (0 v/v% to 40 v/v%, by 10 v/v% interval) at room
temperature (~20 °C). The measured thermophysical properties were close to previously reported values; the thermal conductivity
and thermal diffusivity were linearly proportional to the egg white concentration within the investigation range, while the
specific heat capacity decreased as the egg white concentration increased. Taking account of large differences between real
experiment and ideal model, data variations within 20 % were accepted. |
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