Neuropsychological impairment among manic, depressed, and mixed-episode inpatients with bipolar disorder. |
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Authors: | Basso, Michael R. Lowery, Natasha Neel, Jackie Purdie, Rod Bornstein, Robert A. |
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Abstract: | Previous research has demonstrated broad neurobehavioral abnormalities in bipolar affective disorder (cf. G. Cassens, L. Wolfe, & M. Zola, 1990). However, there have been no comparisons of neuropsychological function across patients with manic, depressed, or mixed subtypes. In the present study, 37 manic, 24 mixed-episode, and 25 depressed bipolar I inpatients and 34 control subjects were administered a brief battery of neuropsychological tests. The multivariate and univariate effects of participant group on the neuropsychological measures were uniformly significant (p |
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Keywords: | bipolar affective disorder neuropsychological funtion manic vs depressed vs mixed subtypes |
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