Antitumor cyclic hexapeptides from rubia plants: history, chemistry, and mechanism (2005-2011) |
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| Authors: | Zhao Si Meng Kuang Bin Fan Jun Ting Yan He Xu Wen Yan Tan Ning Hua |
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| Affiliation: | State Key Laboratory of Phytochemistry and Plant Resources in West China Kunming Institute of Botany Chinese Academy of Sciences Kunming 650201, China. |
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| Abstract: | Rubiaceae-type cyclopeptides (RAs), cyclic hexapeptides from Rubia plants, have shown potential antitumor activity in vitro and in vivo. Based on the review about plant cyclopeptides (Chem. Rev., 2006, 106: 840), this mini-review will highlight new progress on the discovery, synthesis, and mechanism of RAs isolated during 2005 to 2011, covering recent work in our group. |
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