Affine-based registration of CT and MR modality images of human brain using multiresolution approaches: comparative study on genetic algorithm and particle swarm optimization

We present a non-linear 2-D/2-D affine registration technique for MR and CT modality images of section of human brain. Automatic registration is achieved by maximization of a similarity metric, which is the correlation function of two images. The proposed method has been implemented by choosing a realistic, practical transformation and optimization techniques. Correlation-based similarity metric should be maximal when two images are perfectly aligned. Since similarity metric is a non-convex function and contains many local optima, choice of search strategy for optimization is important in registration problem. Many optimization schemes are existing, most of which are local and require a starting point. In present study we have implemented genetic algorithm and particle swarm optimization technique to overcome this problem. A comparative study shows the superiority and robustness of swarm methodology over genetic approach.