壳聚糖缓释膜的制备及性能研究

以壳聚糖为原料, 采用流延法制备了壳聚糖膜, 并与戊二醛交联所制备的膜进行了简单的性能比较,得出实验条件为:壳聚糖质量分数为1 %的溶液, 交联温度为70 ℃以上, 交联时间1 h 以上, 自然晾干或80 ℃烘干,成膜比较好。结果表明, 壳聚糖膜有一定的抗拉强度(最高可达到9.92 MPa)和较好的断裂伸长率(最高可达到11 .75%), 没有耐酸性。而与戊二醛交联后壳聚糖膜的抗拉强度能达到(96 .64 MPa)和断裂伸长率能达到(10 .92 %), 耐酸性能也得到了大大提高。

Research on the Preparation and Performance of Chitosan Membrane

The chitosan membrane and crosslineked were prepared by doctor-blade casting process with chitosan. The chitosan solution concentration as well as temperature capacity of glutaraldehyde crosslinked chitosan membranes have been studied. The best experimental conditions of cross-linking of chitosan film have been obtained as follows: the concentration of chitosan solution is 1%, cross linking temperature would be exceeded 70 ℃, cross linking time must be exceeded 1 h, and to obtain the better film, the dry way would be the nature air dries or drying on the 80 ℃. The results show that chitosan membrane has the highest intensity of 9.92 MPa, the maximum ratio of resistant elongation is 11.75%, and the film has not the acid resistance. Though the cross-linked chitosan with glutaric the highest intensity of dialdehyde can achieve the value 96.64 MPa, the maximum ratio of resistant elongation is 10.92%. The acid resistance of film has been enhanced greatly.