UV-Guided isolation of alantrypinone, a novel Penicillium alkaloid |
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| Authors: | TO Larsen K Frydenvang JC Frisvad C Christophersen |
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| Affiliation: | Mycology Group, Department of Biotechnology, Technical University of Denmark, DK-2800 Lyngby, Denmark. TOL@IBT.DTU.DK |
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| Abstract: | Fumiquinazoline F (1) and alantrypinone (2) have been isolated as the two major metabolites of Penicillium thymicola. The structure of 2, which contains a new ring structure, was elucidated by analysis of spectroscopic data including 2D NMR. The absolute configuration of 2 was established by a single-crystal X-ray diffraction study. |
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