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脂质体载药系统经皮给药的研究进展
引用本文:吕洛,魏少敏,林惠芬,刘玉亮,应康,毛裕民. 脂质体载药系统经皮给药的研究进展[J]. 日用化学工业, 2002, 32(5): 51-54
作者姓名:吕洛  魏少敏  林惠芬  刘玉亮  应康  毛裕民
作者单位:1. 上海家化联合股份有限公司,科研部,上海,200082
2. 复旦大学,生命科学院遗传所遗传工程国家重点实验室,上海,200433
摘    要:脂质体是一类具有特殊性质的磷脂,近几年已开始被广泛用作多种药物的载体。药物经皮给药系统是药剂学中的一新兴的领域,通过脂质体包埋技术制备的各种经皮给药系统同样在我国的制药和化妆品行业得到广泛应用。通过对脂质体的组成及一般特性、脂质体载药系统经皮给药的药剂学促透机制和最新的基础实验和应用研究进展的综合分析后显示,脂质体包裹技术在国内相关领域中的应用将具广阔的前景。

关 键 词:脂质体 载药系统 研究进展 经皮给药 促透技术 药学作用机制 药剂学
文章编号:1001-1803(2002)05-0051-04
修稿时间:2002-02-28

Research advance of liposomes as transdermal drug delivery carrier system
Abstract:The liposome,as a class of phospholipid with outstanding nature has been used in drug carrier system in last years.The transdermal drug delivery system (TDDS) i s a novel kingdom in the pharmacy.Up to date,the various of TDDSs also have bee n gained more and more advance and development by the technology of liposome enca psulation in the fields of medical and cosmetic produce of our country.According to the analyses for the information involved with the character and components of liposomes,and the pharmaceutics mechanism of TDDSs that preparated by the tec hnology of liposome encapsulation,and its newly basic experiment and research pr ogress,the results shown that the technology of liposome encapsulation will be a ppear a wider foreground on the correlated fields of our country in future.
Keywords:cosmetic  liposome  transdermal drug delivery carrier system  application and rese arch
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