1,25(OH)2D3-modulated calcium induced keratinocyte differentiation

The purpose of this study was to provide optometrists with suggested base curves and powers for initial lens choice based on the infant's age. A retrospective chart review of 16 congenital cataract patients fitted at U.C. Davis Eye Clinic between July 1987 and May 1993 was performed. Patients with associated ocular pathologies were excluded. All patients were fitted with a Bausch & Lomb Silsoft lens, a Silicone Elastomer, set at a 3.00 D myopic posture, which was decreased with the child's increasing age and activity. This study provides a graphical approach to pediatric aphakic silicone elastomer contact lens fitting. Best-fit regression lines for both graphs have an r squared value better than 0.9. Optometrists will now be able to reference the Base Curve vs. Age and Power vs. Age graphs to determine the initial lens choice when keratometry is unachievable. Furthermore, the data suggest a need for an increased range of powers provided by the Silicone elastomer lens in order to approximate normal visual development.