脂肪酸碳链长度对甘三酯体外模拟消化的影响

用pH-stat法模拟不同脂肪酸链长甘三酯的人体体外消化过程,从乳化粒径的角度研究脂肪酸碳链长度对甘三酯体外消化速率的影响。结果表明:三辛酸甘油酯(C8)乳化后,平均粒径最小,其他与之碳数相差越多则粒径越大;整体消化过程中三辛酸甘油酯(C8)的消化速率最高,其他与之碳数相差越多则消化速率越小。乳糜微粒的粒径大小与甘三酯的消化速率呈负相关的关系。消化速率的大小顺序为三辛酸甘油酯(C8)三月桂酸甘油酯(C12)三乙酸甘油酯(C2)三硬脂酸甘油酯(C18)。

Effect of carbon chain length of fatty acids on simulated digestion in vitro of triglyceride

The?digestions?in?vitro?of?triglycerides?with?different?carbon?chain?length?of?fatty?acids?in?human?body?were?simulated?by?pH-stat?method.?From?the?perspective?of?the?particle?size?of?emulsion,?the?effect?of?different?carbon?chain?length?of?fatty?acids?on?the?rate?of?digestion?in?vitro?of?triglyceride?was?studied.?The?results?showed?that?after?emulsification,?the?average?particle?size?of?tricaprylin?(C8)?was?minimum;?with?the?increase?of?carbon?number?differences?between?the?other?triglycerides?and?C8,?the?particle?size?increased.?Tricaprylin?(C8)?had?the?highest?rate?of?digestion?in?the?process?of?the?overall?digestion;?with?the?increase?of?carbon?number?differences?between?the?other?triglycerides?and?C8,?the?rate?of?digestion?reduced.?A?negative?correlation?between?particle?size?of?chylomicron?and?digestion?rate?of?triglyceride?was?found.?The?rate?of?digestion?of?tricaprylin?(C8)?was?the?highest,?followed?by?laurin(C12),?triacetin(C2)?and?tristearin(C18).