Microstructures,mechanical and cytocompatibility of degradable Mg–Zn based orthopedic biomaterials |
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Affiliation: | 1. The Conservation Institute of Dunhuang Academy, Dunhuang, 736200 Gansu, China;2. National Research Centre for Conservation of Ancient Wall Paintings, Dunhuang, 736200 Gansu, China |
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Abstract: | The Mg–1Zn–xSr (x = 0.2, 0.5, 0.8 and 1 wt.%) alloys have been prepared by zone purifying solidification followed by backward extrusion (BE). The grain size was reduced and the hardness was improved with the increased concentration of strontium (Sr) after backward extrusion. The BE–Mg–1Zn–0.8Sr alloy was mostly composed of fine precipitates (MgZn and Mg17Sr2) and Mg matrix. At the same time, the mechanical properties of BE–Mg–Zn–Sr alloys were increased with the increment of strontium, which were strongly associated with fine average grain size and homogeneous secondary precipitates. The degradation rate is significantly increased when Sr content is over 0.8 wt.%. The homogenous degradation rate is achieved. The degradation products show good biocompatibility evaluated by MTT method using L929 cell line. It is demonstrated that the micro-alloying element of Sr is a potential approach to develop novel Mg–Zn based biomaterials. |
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Keywords: | Magnesium alloys Microstructure Mechanical properties Corrosion properties Biocompatibility |
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