| 2-氯-6-氟甲苯的合成研究 |
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| 引用本文： | 刘丽荣,王跃君,张所信,周海兵,徐永章. 2-氯-6-氟甲苯的合成研究[J]. 精细化工中间体, 2003, 33(5): 23-24 |
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| 作者姓名： | 刘丽荣 王跃君 张所信 周海兵 徐永章 |
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| 作者单位： | 1. 淮海工学院化工系,江苏,连云港,222005
2. 河北经贸大学附中,河北,石家庄,050061 |
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| 摘 要： | 研究了 2 氯 6 氟甲苯的合成。以铁粉为还原剂 ,在 10 0℃回流的情况下 ,于氯化亚铁水溶液中将原料 2 氯 6 硝基甲苯还原成 2 氯 6 氯基甲苯 ,根据Balz schieman反应 ,再由2 氯 6 氨基甲苯在工业乙醇溶液中重氮化生成氟硼酸重氮盐 ,最后氟硼酸重氮盐于 14 0℃分解得到产物 2 氯 6 氟甲苯 ,总收率为 6 7 98%。产品经气相色谱检测 ,纯度为 99 2 %。
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| 关 键 词： | 2-氯-6-硝基甲苯 2-氯-6-氟甲苯 合成 |
| 文章编号： | 1009-9212(2003)05-0023-02 |
| 修稿时间： | 2002-12-18 |
The Synthesis of 2-Chlor-6-fluorotoluene |
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| LIU Li-rong,WANG Yue-jun,etc. The Synthesis of 2-Chlor-6-fluorotoluene[J]. Fine Chemical Intermediates, 2003, 33(5): 23-24 |
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| Authors: | LIU Li-rong WANG Yue-jun etc |
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| Affiliation: | LIU Li-rong~1,WANG Yue-jun~2,etc |
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| Abstract: | The synthesis method of 2-chloro-6-fluorotoluene was studied. Iron powder was used as reducer ,and 2-chloro-6-nitrotoluene was reduced to 3-chloro-2-methyloniline by being warmed in ferrous chloride aqueous solution.According to the reaction of Balz-schieman, 3-chloro-2-methyloniline was diazoed and cranked out diazo salt of fluoroboric acid, then it was decomposed to 2-chloro-6-fluorotoluene at 140?℃.The productive percentage is 67.98% by gas phase chromaogtraph. The purity of production is 99.2%. The synthetic method of 2-chloro-6-fluorotoluene was suited to industrial production and has high value. In this experiment ,we also approached productive percentage influene with reduatant, temperature ,and time. |
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| Keywords: | chloro-6-fluorotoluene 2-chloro-6-nitrotolu-ene synthesis |
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