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Manipulating Cell Migration and Proliferation with a Light‐Activated Polypeptide |
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| Authors: | Danielle S Miller Dr Sara Chirayil Dr Haydn L Ball Dr Kevin J Luebke Dr |
| Affiliation: | 1. Division of Translational Research, University of Texas Southwestern Medical Center, Dallas, TX 75390‐9185 (USA), Fax: (+1)?214‐648‐4156;2. Protein Technology Center, University of Texas Southwestern Medical Center, Dallas, TX 75390‐9185 (USA) |
| Abstract: | Remote control of cells : A polypeptide has been made that stimulates proliferation and migration of cells upon photochemical activation. This light‐activated polypeptide enables spatially defined control of cell populations at the scale of tissue organization; this is accomplished without physically contacting the cells or modifying their substrate.  |
| Keywords: | caged proteins EGF growth factors photochemistry tissue engineering |