Phase Reversion‐Induced Nanograined/Ultrafine‐Grained Structures in Austenitic Stainless Steel and their Significance in Modulating Cellular Response: Biochemical and Morphological Study with Fibroblasts |
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Authors: | R. Devesh Kumar Misra Wah‐Wah Thein‐Han Mahesh Chandra Somani L. Pentti Karjalainen |
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Affiliation: | 1. Biomaterials and Biomedical Engineering, Research Laboratory, Center for Structural and Functional Materials University of Louisiana at Lafayette, P.O. Box 44130, Lafayette, LA 70504, USA;2. Department of Mechanical Engineering University of Oulu, P.O. Box 4200, Oulu 90014, Finland |
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Abstract: | Materials science, engineering, and biological sciences have been combined to improve the tissue compatibility of medical devices. In this regard, nano/ultrafine structuring of austenitic stainless steel obtained using an innovative approach of “phase‐reversion” has been evaluated for modulation of cellular activity. The biochemical and morphology study with fibroblasts point toward the improvement of tissue compatibility on comparison with coarse‐grained structures, strengthening the foundation of nanostructured materials for bio‐medical applications. |
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