Nitric oxide dose response during moderate and severe hypoxia in swine |
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| Authors: | SG Emil JE Berkeland JB Atkinson |
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| Affiliation: | Institute of Medical Biochemistry and Chemistry, University of Bari, Italy. |
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| Abstract: | ![]()
The vectorial nature of redox Bohr effects (redox-linked pK shifts) in cytochrome c oxidase from bovine heart incorporated in liposomes has been analyzed. The Bohr effects linked to oxido-reduction of heme a and CuB display membrane vectorial asymmetry. This provides evidence for involvement of redox Bohr effects in the proton pump of the oxidase. |
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