| 药物洗脱支架的力学性能分析与优化设计 |
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| 引用本文： | 陈静,邓子辰.药物洗脱支架的力学性能分析与优化设计[J].西北工业大学学报,2011,29(3):385-389. |
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| 作者姓名： | 陈静 邓子辰 |
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| 作者单位： | 1. 西北工业大学力学与土木建筑学院,陕西西安,710072
2. 西北工业大学力学与土木建筑学院,陕西西安710072;大连理工大学工业装备结构分析国家重点实验室,辽宁大连116023 |
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| 基金项目： | 111引智计划，大连理工大学工业装备结构分析国家重点实验室开放基金 |
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| 摘 要： | 药物洗脱支架(DES)由于其卓越的降低再狭窄能力,因而在经皮冠动脉治疗中得到了广泛应用,但也显现出一系列的问题。建立DES模型并进行结构优化从而改善支架结构是一种解决该系列问题的有效途径。文章使用UG软件建立优化后的MAC-J09-3.0支架模型。然后使用有限元分析软件ABAQUS和拓扑优化软件OptiStruct,对支架进行力学性能分析与挖槽设计。将优化后的三种支架进行受力分析与比较发现:通过挖槽设计和优化支撑筋的材料分布,既能增加支架的载药性能又保持了支架的支撑性能。
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| 关 键 词： | 有限元方法 优化 设计 药物洗脱支架 再狭窄 |
Analyzing Mechanical Properties of DES (Drug-Eluting Stent) and Optimizing Its Design |
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| Chen Jing,Deng Zichen.Analyzing Mechanical Properties of DES (Drug-Eluting Stent) and Optimizing Its Design[J].Journal of Northwestern Polytechnical University,2011,29(3):385-389. |
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| Authors: | Chen Jing Deng Zichen |
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| Affiliation: | 1,21.Department of Engineering Mechanics,Northwestern Polythechnical University,Xi′an 710072,China2.State Key Laboratory of Structural Analysis of Industrial Equipment,Dalian University of Technology,Dalian 116023,China |
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| Abstract: | Aim.The introduction of the full paper reviews the development of DES and then points out that the research in this paper is,in our opinion,promising for effectively resolving the restenosis problem from the short-term viewpoint.Sections 1 and 2 explain how we perform our research and present our research results.The core of section 1 consists of:(1) we construct the MAC-J09-3.0 DES model using UG software;(2) we analyze the mechanical properties of the DES with the finite element analysis software ABAQUS a... |
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| Keywords: | finite element method optimization design drug-eluting stent(DES) restenosis |
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