Unilateral enophthalmos secondary to acquired hemilipodystrophy

PURPOSE: To report a case of acquired hemilipodystrophy with ipsilateral enophthalmos. METHODS: Case report. We examined a 25-year-old woman who developed progressive unilateral enophthalmos secondary to fat atrophy on the corresponding left side of her body. RESULTS: Computed tomography confirmed that atrophy in the left orbit, loss of fat in the preorbital area, and partial loss of eyebrow cilia on the same side were present. A biopsy specimen from the left arm was consistent with lipodystrophy. The systemic examination and laboratory values were within normal limits. CONCLUSION: Although it is a rare condition, lipodystrophy may be a cause of unilateral enophthalmos.