G-protein signaling: fine-tuning signaling kinetics |
| |
| Authors: | N Zerangue LY Jan |
| |
| Affiliation: | Howard Hughes Medical Institute, Department of Physiology, University of California San Francisco, California 94143, USA. zerangue@phy.ucsf.edu |
| |
| Abstract: | Mammalian 'regulators of G protein signaling' (RGS proteins) help shut off G-protein-mediated signaling by GTPase activation. But new evidence shows that RGS proteins can also speed up the activation of signaling. The combined effect is a change in signaling kinetics without a decrease in signaling intensity. |
| |
| Keywords: | |
| 本文献已被 PubMed 等数据库收录！ |
|
