Use of an intravascular T1 contrast agent to improve MR cine myocardial-blood pool definition in man |
| |
Authors: | AE Stillman N Wilke M Jerosch-Herold |
| |
Affiliation: | Department of Radiology, University of Minnesota, MN 55305, USA. stillman@sparky.drad.umn.edu |
| |
Abstract: | The feasibility of improving myocardial/blood pool contrast in MR cine images through use of an intravascular contrast agent (Ferumoxtran, Advanced Magnetics, Inc., Cambridge, MA) was tested in four subjects. The contrast-to-noise ratio (CNR) demonstrated a trend toward improvement in the short axis and improved significantly in the long axis cine by an average of 128% (P < .05). Image intensity gradients at the myocardial/blood pool interface increased significantly in both the short and long axis (P < .01). It is expected that larger image intensity gradients at the endocardial border should improve the capabilities of automated segmentation algorithms, reducing the uncertainty and need for manual editing. |
| |
Keywords: | |
本文献已被 PubMed 等数据库收录! |
|