| Ce(Ⅲ)-modulation over non-enzymatic Pt/CeO2/GO biosensor with outstanding sensitivity and stability for lactic acid detection |
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| 作者姓名： | Luyao Zhang Fuli Tian Huan Li Jiangman Meng Qi Liu Xiaoqian Guo Yun Qiu Jun Zhang Changyan Li |
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| 作者单位： | 1. College of Chemistry and Chemical Engineering,Inner Mongolia University;2. Key Laboratory of Medicinal and Edible Plants Resources of Hainan Province,Hainan Vocational University of Science and Technology;3. Department of Materials Science and Engineering,Southern University of Science and Technology |
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| 基金项目： | supported by the National Natural Science Foundation of China (21971129,22067015)；;Scientific Research Projects of Higher Education of Inner Mongolia Autonomous Region(NJZY21285)； |
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| 摘 要： | A series of non-enzymatic graphene functionalized biosensors was developed via deposition precipitation method for lactic acid(LA) detection,which we re characterized by transmission electron micro scopy(TEM),Raman spectroscopy,X-ray photoelectron spectroscopy(XPS),gas chromatography-mass spectrometry,liquid chromatography-mass spectro metry,and proton nuclear magnetic re sonance(1H NMR).The electrochemical performances of the non-enzymatic biosensors were measured by means of the ele...
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| 收稿时间： | 6 April 2022 |
Ce(III)-modulation over non-enzymatic Pt/CeO2/GO biosensor with outstanding sensitivity and stability for lactic acid detection |
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| Luyao Zhang,Fuli Tian,Huan Li,Jiangman Meng,Qi Liu,Xiaoqian Guo,Yun Qiu,Jun Zhang,Changyan Li.Ce(III)-modulation over non-enzymatic Pt/CeO2/GO biosensor with outstanding sensitivity and stability for lactic acid detection[J].Journal of Rare Earths,2023,41(9):1437-1447. |
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| Affiliation: | 1. Department of Engineering and System Science, National Tsing Hua University, Taiwan;2. CNRS, Centre de Nanosciences et de Nanotechnologies, Université Paris-Saclay, Palaiseau, France |
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| Abstract: | A series of non-enzymatic graphene functionalized biosensors was developed via deposition precipitation method for lactic acid (LA) detection, which were characterized by transmission electron microscopy (TEM), Raman spectroscopy, X-ray photoelectron spectroscopy (XPS), gas chromatography-mass spectrometry, liquid chromatography-mass spectrometry, and proton nuclear magnetic resonance (1H NMR). The electrochemical performances of the non-enzymatic biosensors were measured by means of the electrochemical impedance spectroscopy (EIS) and cyclic voltammetry (CV) method. The comprehensive analysis of structures shows that Pt, CeO2, and GO components interact with each other. During the storing and releasing oxygen, the valence ratio of Ce3+/Ce4+ and the number of oxygen vacancies in CeO2 change accordingly, which can be conducive to increasing electronic transmission capacity and finally leads to the improvement of electrocatalytic performance. Among them, the Pt/CeO2/GO biosensor containing 0.47 at% platinum exhibits an excellent electrochemical detection performance with high sensitivity of 12.3 µA·L/ (mmol·cm2) and a low limit of detection (LOD) of 5.12 μmol/L in a wide linear range from 10 to 900 μmol/L. In addition, the proposed biosensor possesses a promising anti-interference capability, as well as high stability and good reproducibility, which was assessed by testing the cyclic voltammogram in 0.1 mol/L lactic acid one year later. The underlying mechanism was proposed for electrochemical oxidation of LA to carbon dioxide and acetic acid with the synergistic effect among Pt, CeO2, and GO. Furthermore, the results of the standard addition method in real samples (human serum and urine samples) reveal that the lactic acid detection of the non-enzymatic Pt/CeO2/GO biosensor is accompanied by high reliability. Thus, it will be a valuable biosensor for in vitro detection of lactic acid level in clinical samples. |
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| Keywords: | Non-enzymatic biosensor Lactic acid Oxygen vacancy Synergistic effect Rare earths |
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