密度法研究防腐剂苯甲酸钠与生物模型化合物的相互作用

用ＡｎｔｏｎＰａａｒＤＭＡ５５型精密数字密度计测定了２９８．１５Ｋ时苯甲酸钠在ＤＭＦ－Ｈ２Ｏ二元混合溶剂中的密度，利用这些数据，得到了苯甲酸钠在无限稀释时的偏摩尔体积和溶剂效应对偏摩尔体积的贡献值。研究结果表明，苯甲酸钠由水向ＤＭＦ－Ｈ２Ｏ混合溶剂迁移的偏摩尔体积在ｘＤＭＦ≈０．０２６７处出现极小值，ｘＤＭＦ≈０．３６５处出现极大值。利用溶质－溶剂相互作用和混合溶剂的结构对结果进行了讨论

Study on the Interaction between Preservative Sodium\=Benzoate and Biological Model Compound with Densimetry

Densities of sodium benzoate were measured in aqueous solutions containing up to 80% DMF at 298.15K with an oscillatingtube densimeter. From these densities, apparent molar volumes of sodium benzoate in DMFH2O mixtures were calculated, partial molar volumes at infinite dilution and contribution of solvent effect to transfer volumes of sodium benzoate were obtained. The transfer partial molar volumes of sodium benzoate from water to DMFH2O mixtures show a minimum near xDMF0.0267 and a maximum near xDMF0.365. This behavior is explained in terms of solutesolvent interaction and solvent structure.