人血中毒物毒品气相色谱检测方法的建立

建立了人体血液中有机磷杀虫剂及毒品类、安眠镇静类药物的气相色谱检测方法。以咖啡因、甲基苯丙胺、氯胺酮、吗啡、安定、苯巴比妥、阿普唑仑、甲拌磷、敌百虫、对硫磷为待测品，利用微珠萃取法，对搅拌提取时间、洗脱溶剂量、pH值、溶液离子强度等方面进行了优化，结果表明人血中上述三类药物的最佳提取条件为：pH值依药物酸碱性而定，搅拌提取30min，洗脱溶剂量1.0mL，回收率均超过70%，相对标准偏差低于5%，达到实际案件分析要求。

Gas Chromatography Analysis Methods for Drugs and Toxicants in Human Blood

Gas chromatography （GC） analysis methods for the determination of organophosphorus insecticide, religious drugs and sedative-hypnotic drugs in human blood were developed. Caffeine, methyl amphetamine, ketamine, mor-phine, tranquillizer, phenobarbital, alprazolam, thimet, dipterex and parathion were selected as the target substances to optimize the extraction conditions of Micro-ball extraction. The parameters included ionic strength,pH value,extraction time and extraction solvent amount. The results indicated that the optimized conditions were as follows：the pH value of sample solution was adjusted according to the acidity and alkalescence of the drug;the vortex mixer shocking time was thirty minutes;the desorption solvent amount was 1.0mL ethanol. The recovery ratios of various drugs were more than 70%,relative standard deviations were less than 5%. It could meet the needs of actual cases.