| 壳聚糖/生物活性玻璃多孔复合支架的制备及界面增强作用 |
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| 引用本文： | 赵娜如,王迎军,梁家瑜,吴峰,康海峰. 壳聚糖/生物活性玻璃多孔复合支架的制备及界面增强作用[J]. 硅酸盐学报, 2010, 0(3) |
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| 作者姓名： | 赵娜如 王迎军 梁家瑜 吴峰 康海峰 |
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| 作者单位： | 华南理工大学;特种功能材料教育部重点实验室;华南理工大学材料科学与工程学院; |
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| 基金项目： | 国家自然科学基金(50702023;50732003;50830101;U083-4003);;国家“973”计划(2005CB623902)资助项目 |
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| 摘 要： | 采用卵磷脂作为表面活性剂对溶胶-凝胶生物玻璃进行表面改性,并采用冷冻干燥法制备用于骨和软骨组织工程的壳聚糖/生物活性玻璃复合多孔支架(chitosan/bioglass porous composite scaffolds,CS/BGS),观察CS/BGS的显微形貌并测定抗压强度,探讨生物玻璃的表面改性对CS/BGS显微结构及力学强度的影响。研究表明:采用冷冻干燥法可以制备具有一定强度的三维连通的CS/BGS,且孔隙率达到90%以上。通过对生物玻璃表面改性可以在一定程度上提高CS/BGS的抗压强度。
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| 关 键 词： | 壳聚糖 溶胶-凝胶生物玻璃 界面增强作用 表面改性 |
PREPARATION AND INTERFACIAL REINFORCED EFFECT OF CHITOSAN/BIOGLASS POROUS COMPOSITE SCAFFOLDS |
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| ZHAO Naru,,WANG Yingjun ,LIANG Jiayu ,WU Feng ,KANG Haifeng. PREPARATION AND INTERFACIAL REINFORCED EFFECT OF CHITOSAN/BIOGLASS POROUS COMPOSITE SCAFFOLDS[J]. Journal of The Chinese Ceramic Society, 2010, 0(3) |
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| Authors: | ZHAO Naru WANG Yingjun LIANG Jiayu WU Feng KANG Haifeng |
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| Affiliation: | 1.Key Laboratory of Specially Functional Materials;South China University of Technology;Ministry of Education;2.College of Materials Science and Engineering;Guangzhou 510640;China |
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| Abstract: | Sol-gel bioglass powders were treated with phosphatidyl cholines,and chitosan/bioglass porous composite scaffolds(CS/BGS) used as bone and cartilage tissue engineering scaffolds were prepared from chitosan and bioglass powders by the freeze-drying technique.The microstructure and compressive strength of the CS/BGS were tested.The effect of surface modification on the microstructures and compressive strength were studied.The results suggest that the CS/BGS with three dimensional connected pores were prepared... |
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| Keywords: | chitosan sol-gel bioglass interfacial reinforced effect surface modification |
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