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Poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) triblock copolymer as a sustained-release carrier for perfume compounds |
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| Authors: | Katsumasa Suzuki Yoshihiro Saito Yoshikazu Tokuoka Masahiko Abe Takatoshi Sato |
| Affiliation: | (1) Faculty of Science and Technology, Science University of Tokyo, Chiba, Japan;(2) College of Pharmacy, Nihon University, 7-1, Narashinodai, 7-Chome, Funabashi-shi, Chiba, Japan |
| Abstract: | The volatility behavior of perfume compounds in poly(ethylene oxide)/poly(propylene oxide)/poly(ethylene oxide) copolymer was investigated by means of dynamic and static headspace analyses. Suppression of the volatility of perfume compounds by EO105PO27EO105 copolymer was markedly greater than by polyethyleneglycol. This suppressive effect may be due to micelle and gel formation of EO105PO27EO105 copolymer. EO105PO27EO105 copolymer is expected to be useful as a novel sustained-release carrier that maintains constant release rates for the volatility of perfume compounds over a wide temperature range. |
| Keywords: | EO105PO27EO105 copolymer headspace analysis perfume compounds solubilization sustained-release carrier volatility |
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