Phase transformation on bone cement: Monocalcium phosphate monohydrate into calcium-deficient hydroxyapatite during setting |
| |
| Authors: | Shyuan-Yow Chen Shih-Fu Ou Nai-Cia Teng Chun-Ming Kung Hsien-Lung Tsai Kuo-Tien Chu Keng-Liang Ou |
| |
| Affiliation: | 1. Department of Dentistry, Cathay General Hospital, Taipei 106, Taiwan;2. Department of Dentistry, Cathay General Hospital, Sijhih, Taipei 221, Taiwan;3. Department of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan;4. Research Center for Biomedical Devices and Prototyping Production, Taipei Medical University, Taipei 110, Taiwan;5. Research Center for Biomedical Implants and Microsurgery Devices, Taipei Medical University, Taipei 110, Taiwan;6. Department of Mold and Die Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan;g Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan;h Division of Prosthodontics, Department of Dentistry, Taipei Medical University Hospital, Taiwan;i Graduate Institute of Biomedical Materials and Tissue Engineering, College of Oral Medicine, Taipei Medical University, Taipei 110, Taiwan |
| |
| Abstract: | This study evaluated the phase transformation of calcium phosphate cement (CPC) using a mixture of monocalcium phosphate monohydrate (MCPM) and CaCO3 as the solid phase and either water or a sodium phosphate buffer (SPB) solution (pH=7.0) as the liquid phase. The synthetic CPC was characterized by X-ray diffraction (XRD) analysis and transmission electron microscopy (TEM). The setting reaction in the SPB solution involved three phase transformations. Firstly, MCPM and CaCO3 reacted with sodium phosphate immediately to form dicalcium phosphate dehydrate (DCPD) which continued to dissolve. Secondly, meanwhile, an intermediate amorphous calcium phosphate (ACP) was formed. Finally, ACP transformed into calcium-deficient hydroxyapatite (CDHA). In contrast, the reaction stopped at the first stage in water. Consequently, the SPB solution not only caused the dissolution of DCPD but also provided the buffering capacity to induce the conversion of the starting materials to CDHA. |
| |
| Keywords: | Calcium phosphate cement Monocalcium phosphate monohydrate Phase transformation Setting reaction |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
