| 血管紧张素转换酶抑制剂和血管肽酶抑制剂研究进展 |
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| 引用本文： | 张小平. 血管紧张素转换酶抑制剂和血管肽酶抑制剂研究进展[J]. 食品与药品, 2006, 8(3): 15-18 |
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| 作者姓名： | 张小平 |
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| 作者单位： | 上海市食品药品监督管理局科技情报研究所,上海,200040 |
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| 摘 要： | 目的介绍治疗高血压和心衰的新方法。通过对国外血管紧张素转换酶抑制剂(ACEI)研究进展的介绍,对照国内此类药物的开发情况,使国内企业对ACEI的开发有较客观的认识。方法根据文献,综述ACEI和血管肽酶抑制剂(VPI)的研究进展。结果VPI同时具有双重抑制中性内肽酶(ACE)和血管紧张素转换酶(NEP)的作用。结论VPI治疗高血压和心衰优于ACEI。
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| 关 键 词： | 血管紧张素转换酶抑制剂 血管肽酶抑制剂 高血压 心衰 研究进展 |
| 文章编号： | 1672-979X(2006)03-0015-04 |
| 修稿时间： | 2005-09-01 |
Investigate of angiotensin-converting enzyme inhibitors (ACEI) and vasopeptidas inhibitors (VPI) |
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| ZHANG Xiao-ping. Investigate of angiotensin-converting enzyme inhibitors (ACEI) and vasopeptidas inhibitors (VPI)[J]. Food and Drug, 2006, 8(3): 15-18 |
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| Authors: | ZHANG Xiao-ping |
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| Abstract: | Objective To introduce new method for treatment hypertension and heart failure . The research and development of angiotensin-converting enzyme inhibitors( ACEI )was compared with World and Chain. In order to be impersonality realized development of relevant ACEI drugs in Chain pharmacy company. Methods The research and development of ACEI and vasopeptidas inhibitors( VPI) were reviewed. Result VPI simulta- neously inhibits ACE and neutral endopeptidase(NEP). Conclusion VPI may be more effective than A ACEI in the treatment of hypertension and heart failure. |
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| Keywords: | ACEI VPI hypertension heart failure research advance |
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