Mathematical modeling and optimization of intratumor drug transport |
| |
| Authors: | D A Klyushin N I Lyashko Yu N Onopchuk |
| |
| Affiliation: | (1) Taras Shevchenko University, Kiev, Ukraine;(2) Cybernetics Institute, National Academy of Sciences of Ukraine, Kiev, Ukraine |
| |
| Abstract: | A pseudohyperbolic problem of optimal control of intratumoral drug distribution is formulated. It takes into account the heterogeneity
of tumor tissues and effects of convection diffusion in a fissured porous medium. A mathematical model constructed and the
corresponding optimal control problem are shown to be correct.
__________
Translated from Kibernetika i Sistemnyi Analiz, No. 6, pp. 147–154, November–December 2007. |
| |
| Keywords: | mathematical model pharmacological drug distribution tumor optimal control pseudohyperbolic problem |
| 本文献已被 SpringerLink 等数据库收录！ |
