Development of a Highly Selective,Sensitive, and Fast Response Upconversion Luminescent Platform for Hydrogen Sulfide Detection |
| |
| Authors: | Juanjuan Peng Chai Lean Teoh Xiao Zeng Animesh Samanta Lu Wang Wang Xu Dongdong Su Lin Yuan Xiaogang Liu Young‐Tae Chang |
| |
| Affiliation: | 1. Singapore Bioimaging Consortium, Agency for Science, Technology and Research (A* STAR), Singapore;2. Department of Chemistry, National University of Singapore, Singapore;3. State Key Laboratory of Chemo/Biosensing and Chemometrics, College of Chemistry and Chemical Engineering, Hunan University, Changsha, Hunan, P. R. China;4. Institute of Materials Research and Engineering, Agency for Science, Technology and Research (A* STAR), Singapore;5. Center for Functional Materials, NUS (Suzhou) Research Institute, Suzhou, Jiangsu, P. R. China |
| |
| Abstract: | Hydrogen sulfide (H2S) has been recognized as one of most important gaseous signaling molecules mediated by a variety of physiological and pathological processes. Yet, its functions remain largely elusive due to the lack of potent monitoring methods. Hereby this issue is addressed with a powerful new platform—dye‐assembled upconversion nanoparticles (UCNPs). A series of chromophores with different absorption bands and fast responses towards H2S is combined with UCNPs and results in a library of H2S sensors with responsive emission signals ranging from the visible to the near‐infrared (NIR) region. These nanoprobes demonstrate highly selective and rapid responses to H2S in vitro and in cells. Furthermore, H2S levels in blood can be detected using the developed nanoprobes. Hence the reported H2S sensing platform can serve as a powerful diagnostic tool to research H2S functions and to investigate H2S‐related diseases. |
| |
| Keywords: | sensor hydrogen sulfide upconversion luminescent platform |
|
|
