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Application of femtosecond laser ablation for detaching grown protein crystals from glass capillary tube |
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| Authors: | Kashii Masafumi Fujisawa Ryo Adachi Hiroaki Mori Yusuke Sasaki Takatomo Koga Yuichi Takano Kazufumi Kanaya Shigenori Matsumura Hiroyoshi Inoue Tsuyoshi Murakami Satoshi Sugamoto Kazuomi Yoshikawa Hideki |
| Affiliation: | Department of Orthopaedic Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan. mkashii-osk@umin.ac.jp |
| Abstract: | We developed a novel technique for detaching protein crystals from glass capillary tube using the counter diffusion crystallization technique by femtosecond laser irradiation. X-ray diffraction analysis demonstrated that femtosecond laser irradiation has little effect on crystallinity. This technique will contribute to progress in structural genomics as a powerful tool. |
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