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Expression of RUNX1-JAK2 in Human Induced Pluripotent Stem Cell-Derived Hematopoietic Cells Activates the JAK-STAT and MYC Pathways |
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| Authors: | Klaus Fortschegger Anna-Maria Husa Dagmar Schinnerl Karin Nebral Sabine Strehl |
| Affiliation: | St. Anna Children’s Cancer Research Institute (CCRI), 1090 Vienna, Austria; (A.-M.H.); (D.S.); (K.N.); (S.S.) |
| Abstract: | |
| Keywords: | leukemia oncogenic fusion CRISPR/Cas9 hematopoiesis hiPSC JAK-STAT signaling MYC pathway |