镉对阉割大鼠前列腺Bcl-2和Bax表达的影响 |
| |
引用本文: | 郭磊磊,周仁江,李庆春,李剑,罗子国.镉对阉割大鼠前列腺Bcl-2和Bax表达的影响[J].四川激光,2012(3):92-94. |
| |
作者姓名: | 郭磊磊 周仁江 李庆春 李剑 罗子国 |
| |
作者单位: | [1]重庆医科大学生命科学院,重庆400016 [2]重庆市九龙坡区第五人民医院,重庆400029 |
| |
摘 要: | 目的:研究不同剂量镉对阉割大鼠前列腺上皮细胞Bcl-2与Bax太达的影响,并探讨其作用机制及与前列腺癌的关系。方法:将60只健康雄性SD大鼠随机分为六组:即对照组、阉割组、低剂量镉组(2.5mμmol/Kg)、高刺时镉组(20mμ mol/Kg)、阉割低剂量镉组(2.5mμmol/kg)、阉割高剂量镉(20mμmol/Kg),18月后取材进行实验。采用免疫组化方法检测不同组别间的Bcl-2和Bax的表达的情况,并进行图像分析。
|
关 键 词: | 镉 去势 前列腺 增殖 凋亡 |
The expression of Bcl - 2 and Bax with cadmium in prostate glands of castrated rats |
| |
Affiliation: | GUO Lei - lei, ZHOU Ben - jiang, LI Qing - chun, LI Jian, LUO Zi - guo( 1. Institute of Life Sciences in Chongqing Mextit:al University, Chongqing 400016, China; 2. The Fifth Hospit',d in JiuLongpo, Chongqing 400029, China) |
| |
Abstract: | Objective: To study the influence of the different doses of eadmium on the expession of Bcl-2 and Bax in prostatic epithelial cells of castrated rats , and explore its mechanism and the relationship to prostate cancer. Methods :Sixty healthy male adult SD r'ats were randomly dividexl into six groups: control group, |
| |
Keywords: | cadmium castration prostate proliferation apoptsis |
本文献已被 维普 等数据库收录! |
|