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K-means聚类数的确定及在细胞图像颜色校正中的应用
引用本文:罗丽丽,蔡坚勇,蔡荣太,林李金,蔡娟.K-means聚类数的确定及在细胞图像颜色校正中的应用[J].计算机系统应用,2014,23(1):114-118.
作者姓名:罗丽丽  蔡坚勇  蔡荣太  林李金  蔡娟
作者单位:福建师范大学 光电与信息工程学院, 福州 350007;福建师范大学 光电与信息工程学院, 福州 350007;福建师范大学 医学光电科学与技术教育部重点实验室, 福州 350007;福建师范大学 福建省光子技术重点实验室, 福州 350007;福建师范大学 智能光电系统工程研究中心, 福州 350007;福建师范大学 光电与信息工程学院, 福州 350007;福建师范大学 福建省光子技术重点实验室, 福州 350007;福建师范大学 光电与信息工程学院, 福州 350007;福建师范大学 光电与信息工程学院, 福州 350007
基金项目:福建省高校产学合作科技重大项目(2011H6010);国家自然科学基金(61179011)
摘    要:针对大量瑞氏染色细胞图像, 通过YCbCr颜色空间进行K-means聚类, 观察各分量聚类中心差值变化规律, 提出了一种新的确定K-means聚类数的颜色校正算法。该算法首先是将瑞氏染色细胞图像中不同目标分别准确地聚集在相应类当中, 再与标准图像中的每类进行配比, 并利用直方图规定化进行直方图调整, 得到颜色校正结果。经大量实验证明, 尤其在细胞图像中目标颜色特征较接近的情况下, 该算法通过确定合适的聚类数可大大提高颜色校正结果的准确率。

关 键 词:K-means  中心差值  聚类数  颜色校正  准确率
收稿时间:2013/7/10 0:00:00
修稿时间:2013/8/19 0:00:00

Determination of Number of Clusters in K-means and Application in Color Correction of Cell Image
LUO Li-Li,CAI Jian-Yong,CAI Rong-Tai,LIN Li-Jin and CAI Juan.Determination of Number of Clusters in K-means and Application in Color Correction of Cell Image[J].Computer Systems& Applications,2014,23(1):114-118.
Authors:LUO Li-Li  CAI Jian-Yong  CAI Rong-Tai  LIN Li-Jin and CAI Juan
Affiliation:College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, China;College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, China;Key Laboratory of Optoelectronic Science and Technology for Medicine Ministry of Education, Fujian Normal University, Fuzhou 350007, China;Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou 350007, China;Intelligent Optoelectronic Systems Research Centre, Fujian Normal University, Fuzhou 350007, China;College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, China;Fujian Provincial Key Laboratory for Photonics Technology, Fujian Normal University, Fuzhou 350007, China;College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, China;College of Photonic and Electronic Engineering, Fujian Normal University, Fuzhou 350007, China
Abstract:To observe the changing rule of clustering center’s value in K-means by the YCbCr color space, against a lot of cell image by Wright Stain, this paper proposed a new method to determine the number of clusters in K-means to get a good result of color correction. Different target of cell image could be firstly gathered in the corresponding class accurately, then by matching between classes, and using histogram specification for adjusting histogram, the results of color correction could at last be achieved. It has been proved by many experiments that this algorithm can greatly improve the accuracy of color correction results, especially the target with closer color features in cell.
Keywords:k-means  center’s value  number of clusters  color correction  accuracy
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