| A NEW APPROACH TO THE CURVE FITTING OF IN VITRO RADIOASSAYS BASED ON THE MASS ACTION LOW |
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| 作者姓名： | 夏宗勤 |
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| 作者单位： | Shanghai Second |
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| 摘 要： | A new curve fitting method with its mathematical models derived from the mass action law is presented which is applicable to several in vitro radioassays including RIA and RBA. Experiments revealed that the robustness of this method is better than the conventional methods like Woolf plot in RBA and 4- parameter logistic plot in RIA. However, the robustness of this method is only relative: in some cases of RIA and RBA, the bias of the results may still be too large to be acceptable. Further improvement is expected to be studied.
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A NEW APPROACH TO THE CURVE FITTING OF IN VITRO RADIOASSAYS BASED ON THE MASS ACTION LOW |
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| Xia Zongqin.A NEW APPROACH TO THE CURVE FITTING OF IN VITRO RADIOASSAYS BASED ON THE MASS ACTION LOW[J].Nuclear Science and Techniques,1990(3). |
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| Authors: | Xia Zongqin |
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| Abstract: | A new curve fitting method with its mathematical models derived from the mass action law is presented which is applicable to several in vitro radioassays including RIA and RBA. Experiments revealed that the robustness of this method is better than the conventional methods like Woolf plot in RBA and 4- parameter logistic plot in RIA. However, the robustness of this method is only relative: in some cases of RIA and RBA, the bias of the results may still be too large to be acceptable. Further improvement is expected to be studied. |
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| Keywords: | Vitro radioassays Curve fitting Mathematical models Mass action law |
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